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TB-500 (Thymosin Beta-4) is a 43 amino acid peptide sequence. Thymosin Beta-4 is a hormone secreted from the thymus. Its primary function is to stimulate the production of T cells, which are an important part of the immune system.
In animal models, Thymosin Beta-4 has been shown to improve blood vessel growth, regulate wound healing, decrease inflammation, and reduce oxidative damage. Thymosin-beta-4 has a role in protection, tissue repair, regeneration and remodelling of injured tissues. It is also of active interest in anti-ageing research.
Thymosin also assists in the development of B cells to plasma cells to produce antibodies. The predominant form of thymosin, thymosin beta-4, is an actin, a cell-building protein.
TB-500 peptide (Thymosin Beta-4) has been shown to:
Encourages tissue repair
Increases cells in healing
Promotes angiogenesis (blood vessel formation)
Decreases inflammation
Improved muscle tone
Stretches connective tissue
Helps maintain flexibility
Increased endurance and strength
Soft tissue repair – tendon, ligament, muscle sports, and athletic injuries
Accelerates hair growth
Reduces scar tissue
This product is prepared for RESEARCH USE ONLY and may not be used for other purposes.
TB-500 is a synthetic analogue to a naturally occurring protein present in most kinds of mammalian tissue. The main purpose of this peptide is to promote healing. The healing effects of TB-500 have been observed in tendons, ligaments, muscles, skin, heart, and eyes. It aids in the quick healing of wounds by promoting new blood vessels and muscle fibre growth. It upregulates cell-building proteins like actin.
TB-500 peptides’ property of enhancing muscle growth in both healthy and damaged tissues has led to its application as an experimental therapeutic in animal test subjects with muscular dystrophy. Administration of TB-500 allowed animal test subjects with muscular dystrophy to achieve improved maintenance of muscle growth and development, even in the absence of important, naturally occurring proteins that usually guide this action.
TB500 has also been researched to be an aid in the healing of heart tissue following a heart attack and as a very powerful agent for quickly healing skin abrasions. TB500’s angiogenic (blood vessel-forming) properties are responsible for its excellent application in these areas.
Structure
Synonyms
Thymosin Beta 4
77591-33-4
THYMOSIN BETA 4 ACETATE
([13C6]Leu17)-Thymosin b4 (human, bovine, horse, rat) trifluoroacetate salt Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-[13C6]Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH trifluoroacetate salt
Thymosin b4 (cattle)
Hinkel R, Klett K, Bähr A, Kupatt C. Thymosin β4-mediated protective effects in the heart. Expert Opin Biol Ther. 2018 Jul;18(sup1):121-129. doi:10.1080/14712598.2018.1490409.
Bjørklund G, Dadar M, Aaseth J, Chirumbolo S. Thymosin β4: a multi-faceted tissue repair stimulating protein in heart injury. Curr Med Chem. 2019 Jul 16. doi: 10.2174/0929867326666190716125456.
Michael Chopp 1, Zheng Gang Zhang. Thymosin β4 as a restorative/regenerative therapy for neurological injury and neurodegenerative diseases. DOI: 10.1517/14712598.2015.1005596
Karina N Dubé, Nicola Smart, Thymosin β4 and the vasculature: multiple roles in development, repair and protection against disease
PMID: 30063849 DOI: 10.1080/14712598.2018.1459558
All articles and product information on this website are for educational purposes only. These products are not medicines or drugs and have not been approved to treat or cure any medical condition.
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Products shown on this website are prepared for RESEARCH USE ONLY and may not be used for other purposes.
