Ipamorelin — one of the cleanest, most selective growth hormone research peptides, studied for stimulating GH release without the cortisol or prolactin rise seen with older compounds. ≥99% purity. Fast UK dispatch, free delivery.
Original price was: £24.99.£19.99Current price is: £19.99.
-21%Ipamorelin is one of the most selective growth hormone research peptides available — known as the “clean” GH secretagogue because it stimulates growth hormone release without the cortisol, prolactin or appetite increase seen with older peptides such as GHRP-2 and GHRP-6.
In animal research, Ipamorelin has been studied for its role in:
Ipamorelin is most often researched alongside CJC-1295 (No DAC) — the two work through separate pathways and are studied together for their combined effect on GH output. See the CJC-1295 & Ipamorelin bundle or the CJC-1295 (No DAC) page. For reconstitution, bacteriostatic water and syringes are available separately.
These products are supplied strictly for laboratory research and development purposes only. Not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease.
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue, first described by Raun and colleagues in 1998 as “the first selective growth hormone secretagogue.” It remains one of the most extensively characterised compounds of its class in the published research literature.
Ipamorelin mimics the hormone ghrelin at the growth hormone secretagogue receptor (GHSR-1a) on pituitary cells, triggering a pulse of growth hormone release. It acts on a different receptor from GHRH analogues such as CJC-1295, which is why the two are frequently studied together.
Its selectivity is its defining feature. In the foundational research, Ipamorelin released growth hormone without meaningfully raising cortisol, ACTH or prolactin — even at doses far above the level needed for GH release. Older growth hormone-releasing peptides don’t share this clean profile.
| Compound | GH release | Cortisol / ACTH | Prolactin | Appetite |
|---|---|---|---|---|
| Ipamorelin | Strong, selective | Minimal | Minimal | Minimal |
| GHRP-2 | Strong | Elevated | Elevated | Increased |
| GHRP-6 | Strong | Elevated | Elevated | Strongly increased |
In preclinical and animal research, Ipamorelin has been studied for a role in:
Ipamorelin acts on the ghrelin receptor (GHSR-1a); CJC-1295 (No DAC) acts on the GHRH receptor. Because the two pathways are separate but converge on the same GH-secretory machinery, activating both together has been shown in preclinical models to produce greater GH pulse amplitude than either alone. This is why the pairing is the reference GH-axis research combination — available together as the CJC-1295 & Ipamorelin bundle.
Further reading: Mixing CJC-1295 and Ipamorelin: same syringe, same vial, or separate?
Supplied as a lyophilised powder. Store sealed, protected from light and moisture; refrigerate after reconstitution. Supplied strictly for laboratory research and development purposes only. Not for human or animal consumption, diagnosis, treatment, or prevention of any disease.
Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.85 g/mol
CAS Number: 170851-70-4
Synonyms: 170851-70-4 · Ipamorelin · NNC 26-0161
PubChem CID: 9831659
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
These products are supplied strictly for laboratory research and development purposes only. Not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease.
